Synthesis of novel, highly reactive 1-oxyl-2,2,6,6-tetramethyl-1,2,5,6-tetrahydropyridine derivatives
نویسندگان
چکیده
منابع مشابه
Reactions of Nitroxides. Part XII [1]. – 2,2,6,6-Tetramethyl-1-oxyl- 4-piperidyl Chloroformate – A New Reactive Nitroxyl Radical. A One-pot Synthesis of 2,2,6,6-Tetramethyl-1-oxyl-4-piperidyl N,N-Dialkyl-carbamates
The reactive nitroxides 2,2,6,6-tetramethyl-1-oxyl-4-piperidyl chloroformate and 2,2,6,6-tetramethyl-1-oxyl-4-piperidyl chlorothionoformate were synthesized from 2,2,6,6-tetramethyl-4-hydroxypiperidin-1-oxyl and diphosgene (68%) or thiophosgene (61%), respectively. The reactions of the chloroformate and chlorothionoformate with lower secondary amines lead to 2,2,6,6-tetramethyl-1-oxyl-4-piperid...
متن کاملThe crystal and molecular structure of the potassium salt of 2,2,5,5-tetramethyl-3-carboxypyrroline-1-oxyl.
The crystal structure of the potassium salt of 2,2,5,5-tetramethyl-3-carboxypyrroline-1-oxyl (I), which is a free radical of the nitroxide type, has been determined by three-dimensional X-ray methods. The unit cell contains two crystallographically different types of molecule, one of which lies with its five-membered ring entirely in a mirror plane and is therefore perfectly flat. Molecules of ...
متن کاملDecrease in 2,2,6,6-Tetramethyl-Piperidine-1-Oxyl (TEMPO) EPR Signal in Peroxynitrite-Treated Erythrocyte Membranes.
The treatment of erythrocyte membranes with peroxynitrite (ONOO-), a cytotoxic species formed in vivo by the almost completely diffusion controlled reaction of nitric oxide (NO*) and the superoxide anion (O2*-), led to the loss of the EPR signal of the nitroxide radical 2,2,6,6-tetramethyl-piperidine-1-oxyl (TEMPO). The decrease in the TEMPO EPR signal was peroxynitrite concentration dependent ...
متن کامل4,4,5,5-Tetramethyl-2-(4-pyridinio)imidazoline-1-oxyl-3-oxide chloride
The title compound C(12)H(17)N(3)O(2) (+)·Cl(-) consists of a discrete [NITpPyH](+) cation [NITpPy = 2-(4'-pyrid-yl)-4,4,5,5-tetra-methyl-imidazoline-1-oxyl-3-oxide] and a chloride anion. The NITpPy mol-ecule is protonated at the N atom of the pyridyl ring. The anions and cations are connected via N-H⋯Cl hydrogen bonds.
متن کاملSynthesis of Thiazole Derivatives via Multicomponent Reaction of Tetramethyl thiourea using Water as a Safe Solvent
An efficient synthesis of 1,3-thiazole drivatives is described via a three component reaction isothiocyanates, tetramethyl thiourea and ethyl bromopyruvate.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1985
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v85-156